BIOAVAILABILITY OF US COMMERCIAL MAGNESIUM...

BIOAVAILABILITY OF US COMMERCIAL MAGNESIUM PREPARATIONS.

Revista Magnesium Reserch – volume 14 – ano 2001 Número 4; páginas 257- 261.
 
Autores:

1) uhammad Firoz – Department of Veterans Affairs Medical Center, northport, New York, NY 11768.
 
2) Mark Graber -  Department of Medicine, SUNY at Stony Brook, New York, USA.
  
Summary:
 Magnesium deficiency is seen with some frequency in the outpatient setting and requires oral repletion or maintenance therapy. The purpose of this study was to measure the bioavailability of four commercially – available preparations of magnesium, and to test the claim that organic salts are more easily absorbed. Bioavailability was measured as the increment of urinary magnesium excretion in normal volunteers given approximately 21 mEq/day of the test preparations. Results indicated relatively poor bioavailability of magnesium oxide (fractional absorption 4 per cent) but significantly higher and equivalent bioavailability of magnesium chloride, magnesium lactate and magnesium aspartate. We conclude that there is relatively poor bioavailability of magnesium choloride, magnesium lactate and magnesium aspartate. We conclude that there is relatively poor bioavailability of magnesium oxide, but greater and equivalent bioavailability of magnesium chloride, lactate, and aspaertate. Inorganic magnesium salts, depending on the preparation, may have bioavailability equivalent to organic magnesium salts.