
EFFECT OF MAGNESIUM SUPPLEMENTATION CONTAINING MINERAL BISHOFIT (MgCl2.6H2O) SOLUTION AND PYRIDOXINE HYDROCHLORIDE ON ERYTHROCYTE MAGNESIUM DEPLETION AND BEHAVIOR OF RATS AFTER THREE-MONTH ALCOHOLIZATION.
Revista Magnesium Reserch – volume 15 – ano 2002 Número 3/4; páginas 179-189.
Autores:
1)Igor N. Iezhitsa – Medical Academy, Research Institute of Pharmacology, 1 Pavshikh Bortsov sq., Volgograd, 400066 Russia
2)Natalia V. Onishchenko - Medical Academy, Research Institute of Pharmacology, 1 Pavshikh Bortsov sq., Volgograd, 400066 Russia
3)Natalia V. Churbakova- Medical Academy, Research Institute of Pharmacology, 1 Pavshikh Bortsov sq., Volgograd, 400066 Russia
4)Valentine V. Parshev- Medical Academy, Research Institute of Pharmacology, 1 Pavshikh Bortsov sq., Volgograd, 400066 Russia
5)Vladimir I. Petrov- Medical Academy, Research Institute of Pharmacology, 1 Pavshikh Bortsov sq., Volgograd, 400066 Russia
6)Alexander A. Spasov - Medical Academy, Research Institute of Pharmacology, 1 Pavshikh Bortsov sq., Volgograd, 400066 Russia
Summary:
In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2.6h20) and pyridoxine hydrochloride led both to restoration of magnesium level, and to some correction oh behavioural disturbances of animals during chronic alcoholization.