EFFECTS OF HIGHT DOSES OF MAGNESIUM IN DRINKING WATER...

EFFECTS OF HIGHT DOSES OF MAGNESIUM IN DRINKING WATER AND VOLUNTARY WHEEL RUNNING ON MAGNESIUM AND CALCIUM CONCENTRATIONS IN RATS.

Revista Magnesium Research – volume 15 – ano 2002 Número 3/4; paginas 167-172.

Autores:
 

1)S.C. Meludu – Lab. Fatigue Physiology, The National Institute of health and nutition, Tokyo, Japan and 
   Department of  Human Biochemistry. 

2)M. Nishimuta- Lab. Fatigue Physiology, The National Institute of health and nutition, Tokyo, Japan

3)N.A. Aboh- Department of  Human Biochemistry of The National Institute of health and nutition, Tokyo,
   Japan

4)C. Okonkwo- Department of  Human Biochemistry of The National Institute of health and nutition, 
    Tokyo, Japan

5)C.E. Dioka – Department of Chemical Patholog; Nnamdi Azikiwe University; Nnewi, Nigeria. 
 

Summary:

The effect high magnesium intake in addition to supplementation and voluntary wheel activity on magnesium and calcium homeostasis was investigated in rats. Thirty-six 5 –week-old male wistar rats were divided into into four groups  (n = 9). Groups 2 and 4 received five hundred ppm of elemental magnesium as MgCl2 provided in drinking water. After 1 week of acclimatization and 4 weeks of supplement and/or exercise, the animals were fasted and sacrificed.
It appears that magnesium supplementation as well as exercise played some significant role in the homeostatic changes of magnesium and calcium. This could be of great significance in better understanding of mineral homeostasis particularly in sports medicine.